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KMID : 1011420090140030103
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Journal of Korean Ophthalmic Optics Society
2009 Volume.14 No. 3 p.103 ~ p.108
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Relations of Cataract to Metabolic Syndrome and its Components -Based on the KNHANES 2005, 2007-
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Park Sang-Shin
Lee Eun-Hee
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Abstract
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Purpose: This study was performed to assess the effects of metabolic syndrome and its components to cataract.
Methods: We investigated the relation of metabolic syndrome and its components to cataract using data for 2,120 adults, aged 60 years or older, from the Korean National Health and Nutrition Examination Survey 2005, 2007. Using multiple logistic regression analysis, we presented significant odds ratio (OR) increase of cataract according to the number of metabolic abnormalities (1, 2, 3, 4). We also analyzed OR by the prevalence of metabolic components, and analyzed the effects of metabolic medication intakes to cataract prevalence using multiple logistic regression analysis.
Results: The risk of cataract development was significantly increased according to the number of metabolic abnormalities, after adjusting for age, sex, life style, and social economic status variables (p for trend <0.0001). In metabolic components, the disturbances of blood pressure (OR(95% Confidence Interval): 1.32(1.05,1.65)) and fasting glucose (1.35(1.09,1.67)) significantly increased the prevalence of cataract after adjusting for age and sex. Among these metabolic components, the significance of fasting glucose (1.26(1.01, 1.58)) was remained after adjusting for the other variables. Medication intake of hypertensive also increased the risk of cataract (1.49(1.14,1.96)).
Conclusions: Metabolic syndrome and its components increased the risk of cataract, and some medication for treating hypertension was also associated with the cataract incidence.
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KEYWORD
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Cataract, Metabolic syndrome, Blood pressure, Glucose, Obesity
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